| Actor/Actress |
Role |
| Chris Pine |
James T. Kirk |
| Zachary Quinto |
Spock |
| Zoe Saldana |
Nyota Uhura |
| Karl Urban |
Dr. Leonard 'Bones' McCoy |
| Simon Pegg |
Montgomery 'Scotty' Scott |
| John Cho |
Hikaru Sulu |
| Benedict Cumberbatch |
Khan Noonien Singh |
| Anton Yelchin |
Pavel Chekov |
| Bruce Greenwood |
Christopher Pike |
| Peter Weller |
Alexander Marcus |
| Alice Eve |
Carol Marcus |
| Noel Clarke |
Thomas Harewood |
| Nazneen Contractor |
Rima Harewood |
| Amanda Foreman |
Ensign Brackett |
| Aisha Hinds |
Navigation Officer Darwin |
| Joseph Gatt |
Science Officer 0718 |
| Sean Blakemore |
Klingon |
| Nick E. Tarabay |
Klingon |
| Beau Billingslea |
Captain Abbot |
| Deep Roy |
Keenser |
| Chris Hemsworth |
George Kirk |
| Jack Laufer |
Doctor |
| Katie Cockrell |
Girl |
| Kellie Cockrell |
Girl |
| Jennifer Morrison |
Winona Kirk |
| Leonard Nimoy |
Spock Prime |
| Kimberly Arland |
Madeline |
| Jonathan Dixon |
Ensign Froman |
| Jeremy Raymond |
Lead Nibiran |
| Jay Scully |
Lieutenant Chapin |
| Tony Guma |
Nibiran |
| Anjini Taneja Azhar |
Lucille Harewood |
| Jason Matthew Smith |
Cupcake |
| Seth Ayott |
U.S.S. Enterprise Shuttle Ensign |
| Marco Sanchez |
Torpedo Security |
| Lee Reherman |
Uniformed Mercenary |
| Scott Lawrence |
U.S.S. Vengeance Officer |
| Usman Ally |
U.S.S. Vengeance Officer |
| Nolan North |
U.S.S. Vengeance Bridge Officer |
| James Hiroyuki Liao |
U.S.S. Vengeance Bridge Officer |
| Rob Moran |
U.S.S. Vengeance Ensign |
| Akiva Goldsman |
Starfleet Admiral |
| Gianna Simone |
U.S.S. Enterprise Bridge Crew |
| Rene Rosado |
U.S.S. Enterprise Bridge Crew |
| Berit Francis |
Starfleet Admiral |
| Benjamin P. Binswanger |
Starfleet Admiral |
| Christopher Doohan |
Transport Officer |
| Andy Demetrio |
U.S.S. Enterprise Bridge Crew |
| Jacquelynn King |
U.S.S. Enterprise Bridge Crew |
| Long Tran |
U.S.S. Enterprise Bridge Crew |
| Ningning Deng |
U.S.S. Enterprise Bridge Crew |
| Jodi Johnston |
U.S.S. Enterprise Bridge Crew |
| Colleen Harris |
Lady V |
| Jeff Chase |
U.S.S. Enterprise Security |
| Ser'Darius Blain |
U.S.S. Enterprise Red Shirt |
| Heather Langenkamp |
Moto |
| Melissa Paulo |
Bar Girl |
| Cynthia Addai-Robinson |
San Francisco Woman |
| Monisola Akiwowo |
U.S.S. Enterprise Nurse |
| Paul K. Daniel |
Shuttle Pilot |
| Drew Grey |
San Francisco Bar Patron |
| David C. Waite |
U.S.S. Enterprise Crew |
| Douglas Weng |
U.S.S. Vengeance Security |
| Charlie Haugk |
San Francisco Resident |
| Max Chernov |
San Francisco Resident |
| Marc Primiani |
San Francisco Resident |
| Jesper Inglis |
San Francisco Resident |
| Jacob Rhodes |
Nibiru Child |
| Kentucky Rhodes |
Nibiru Child |
| Anthony Wilson |
Shaku |
| Eric Greitens |
Starfleet Ceremonial Guard |
| Melissa Steinman |
Starfleet Ceremonial Guard |
| Adam McCann |
Starfleet Ceremonial Guard |
| Jon Orvasky |
Starfleet Ceremonial Guard |
| Gerald W. Abrams |
Starfleet Memorial Admiral |
| James McGrath |
Starfleet Memorial Admiral |
| Brian T. Delaney |
Additional Voices (voice) |
| Arlen Escarpeta |
Additional Voices (voice) |
| Joe Moses |
Additional Voices (voice) |
| Kevin Michael Richardson |
Additional Voices (voice) |
| David Sobolov |
Additional Voices (voice) |
| Matthew Wood |
Additional Voices (voice) |
| Fred Tatasciore |
Additional Voices (voice) |
| Kiff VandenHeuvel |
Additional Voices (voice) |
| Audrey Wasilewski |
Additional Voices (voice) |
| Bill Hader |
Additional Voices (voice) |
| Tom Archdeacon |
Ensign Spyke (uncredited) |
| Jon Lee Brody |
U.S.S. Enterprise Security (uncredited) |
| Britanni Johnson |
NYU Nurse (uncredited) |
| Hiram A. Murray |
Bar Patron (uncredited) |
| Chris Gardner |
Additional Voices (voice) |
| Julianne Buescher |
Additional Voices (voice) |
| Joe Hanna |
Additional Voices (voice) |
| David Acord |
Additional Voices (voice) |
| Ellie Newlands |
Additional Voices (voice) |
| Candice Renee |
Additional Voices (voice) |
| Emily Towers |
Additional Voices (voice) |
| Gina Hirsch |
Additional Voices (voice) |
