| Actor/Actress |
Role |
| Dwayne Johnson |
Dr. Smolder Bravestone |
| Kevin Hart |
Franklin 'Mouse' Finbar |
| Jack Black |
Professor Sheldon 'Shelly' Oberon |
| Karen Gillan |
Ruby Roundhouse |
| Awkwafina |
Ming |
| Nick Jonas |
Jefferson 'Seaplane' McDonough |
| Alex Wolff |
Spencer Gilpin |
| Morgan Turner |
Martha Kaply |
| Madison Iseman |
Bethany |
| Ser'Darius Blain |
Anthony 'Fridge' Johnson |
| Danny DeVito |
Eddie |
| Danny Glover |
Milo |
| Rhys Darby |
Nigel Billingsley |
| Colin Hanks |
Alex |
| Rory McCann |
Jurgen the Brutal |
| Marin Hinkle |
Spencer's Mom |
| Vince Pisani |
Pharmacy Manager |
| Dorothy Steel |
Village Elder |
| Dania Ramirez |
Lady in Red |
| Derek Russo |
Key Master |
| Nick Gomez |
Oasis Drunk |
| Morgan Brown |
Fortress Guard |
| Deobia Oparei |
Elevator Guard |
| Leslie Simms |
Cake Lady |
| John Ross Bowie |
Cavendish |
| Lucy DeVito |
Maiden |
| Bebe Neuwirth |
Nora |
| Lamorne Morris |
Heater Repair Guy |
| Darin Ferraro |
The Gun Seller (uncredited) |
| Sal Longobardo |
Tony (uncredited) |
| Massi Furlan |
Switchblade (uncredited) |
| Michael Beasley |
Coach Davis (uncredited) |
| Charles Green |
Bartender (uncredited) |
| James William Ballard |
Bad Guy in Fortress (uncredited) |
| Marque Hernandez |
Gypsy Guy in Tattoo Chair (uncredited) |
| Kodai Yamaguchi |
Jumanjian Villager (uncredited) |
| Ashley Scott |
Ashley (uncredited) |
| Melissa Kennemore |
Marauder 1 / Jergens Inner Circle (uncredited) |
| Jennifer Patino |
Bravestone's Mother |
| Madison Johnson |
Little Bethany Vreeke |
| Vanessa Cater |
Red Headed Marauder |
| Javier Villamil |
Switchblade's Sidekick |
| Anthony Neves |
Jurgen's Patrolman |
| John David Bulla |
Groovy Face Tattoo Biker |
| Ryan Cheeseman |
Marauder |
| Cruz Abelita |
Messenger Boy (uncredited) |
| Sheril Rodgers |
New York City Pedestrain (uncredited) |
