| Actor/Actress |
Role |
| Keanu Reeves |
John Wick |
| Michael Nyqvist |
Viggo Tarasov |
| Alfie Allen |
Iosef Tarasov |
| Willem Dafoe |
Marcus |
| Ian McShane |
Winston |
| Lance Reddick |
Hotel Manager / Charon |
| Dean Winters |
Avi |
| Adrianne Palicki |
Ms. Perkins |
| Omer Barnea |
Gregori |
| Toby Leonard Moore |
Victor |
| Daniel Bernhardt |
Kirill |
| Bridget Moynahan |
Helen |
| John Leguizamo |
Aurelio |
| Bridget Regan |
Addy |
| Keith Jardine |
Kuzma |
| Tait Fletcher |
Nicholai |
| Kazy Tauginas |
Ivan (as Kazimieras Tauginas) |
| Alexander Frekey |
Alexander |
| Thomas Sadoski |
Jimmy |
| Randall Duk Kim |
Continental Doctor |
| David Patrick Kelly |
Charlie |
| Clarke Peters |
Harry |
| Kevin Nash |
Francis |
| Gameela Wright |
Delivery Woman |
| Vladislav Koulikov |
Pavel |
| Munro M. Bonnell |
Priest |
| Patricia Squire |
Elderly Woman (as Pat Squire) |
| Vladimir Troitsky |
Team Leader |
| Tommy Bayiokos |
Russian Sniper (uncredited) |
| Carolyn Blair |
Red Circle Club Goer (uncredited) |
| Samantha Crawford |
Red Circle Club Goer (uncredited) |
| Nadia Kay |
Hot Girl (uncredited) |
| Natalia Kiriya |
Red Circle Model (uncredited) |
| Scott Tixier |
Violinist (uncredited) |
