| Actor/Actress |
Role |
| Owen Wilson |
Lightning McQueen (voice) |
| Paul Newman |
Doc Hudson (voice) |
| Bonnie Hunt |
Sally Carrera (voice) |
| Larry the Cable Guy |
Mater (voice) |
| Tony Shalhoub |
Luigi (voice) |
| Cheech Marin |
Ramone (voice) |
| Michael Wallis |
Sheriff (voice) |
| George Carlin |
Fillmore (voice) |
| Paul Dooley |
Sarge (voice) |
| Jenifer Lewis |
Flo (voice) |
| Guido Quaroni |
Guido (voice) |
| Richard Petty |
The King (voice) |
| Michael Keaton |
Chick Hicks (voice) |
| Katherine Helmond |
Lizzie (voice) |
| John Ratzenberger |
Mack /Hamm Car/Abominable Snow Plow/P.T. Flea Car (voice) |
| Joe Ranft |
Red (voice) |
| Jeremy Piven |
Harv (voice) |
| Jeremy Clarkson |
British Harv |
| Dale Earnhardt Jr. |
Junior (voice) |
| Mario Andretti |
Himself |
| Michael Schumacher |
Michael Schumacher Ferrari (voice) |
| Jay Leno |
Jay Limo (voice) |
| Tom Hanks |
Woody Car (voice) |
| Tim Allen |
Buzz Lightyear Car (voice) |
| Billy Crystal |
Mike Car (voice) |
| John Goodman |
Sullivan Truck (voice) |
| Dave Foley |
Flik Car (voice) |
| Bob Costas |
Bob Cutlass (voice) |
| Darrell Waltrip |
Darrell Cartrip (voice) |
| Richard Kind |
Van (voice) |
| Edie McClurg |
Minny (voice) |
| Humpy Wheeler |
Tex (voice) |
| Tom Magliozzi |
Rusty Rust-eze (voice) |
| Ray Magliozzi |
Dusty Rust-eze (voice) |
| Lynda Petty |
Mrs. The King (voice) |
| Andrew Stanton |
Fred (voice) |
| Sarah Clark |
Kori Turbowitz (voice) |
| Mike Nelson |
Not Chuck (voice) |
| Joe Ranft |
Peterbilt (voice) |
| Jonas Rivera |
Boost (voice) |
| Lou Romano |
Snotrod (voice) |
| Adrian Ochoa |
Wingo (voice) |
| E.J. Holowicki |
DJ (voice) |
| Elissa Knight |
Tia (voice) |
| Lindsey Collins |
Mia (voice) |
| Larry Benton |
Motorhome Race Fan (voice) |
| Douglas Keever |
Motorhome Race Fan (voice) |
| Sherry Lynn |
(voice) |
| Mickie McGowan |
Additional Voices (voice) |
| Jack Angel |
Additional Voices (voice) |
| Michael Bell |
Houser Boon (voice) |
| Bob Bergen |
Various Reporters (voice) |
| Susan Blu |
(voice) |
| Andrea Boerries |
(voice) |
| Marco Boerries |
(voice) |
| Rodger Bumpass |
Wide Chick Pitty (voice) |
| Torbin Xan Bullock |
(voice) |
| Richard Cawood |
(voice) |
| Scott Clark |
(voice) |
| Kathy Coates |
Kathy Copter (voice) |
| John Cygan |
Various Reporters (voice) |
| Jennifer Darling |
Various Reporters (voice) |
| Paul Eiding |
Various Reporters (voice) |
| Bill Farmer |
Various Reporters (voice) |
| Brian Fee |
(voice) |
| Teresa Ganzel |
(voice) |
| Craig Good |
Announcer (voice) |
| Jess Harnell |
Sven 'The Governator' (voice) |
| Artie Kempner |
(voice) |
| Hooman Khalili |
Hooman (voice) |
| Sonoko Konishi |
Chuki (voice) |
| Erik Langley |
(voice) |
| Danny Mann |
Al Oft (voice) |
| Laraine Newman |
Various Reporters (voice) |
| Teddy Newton |
(voice) |
| Colleen O'Shaughnessey |
(voice) |
| Bob Peterson |
(voice) |
| Steve Purcell |
(voice) |
| Jan Rabson |
Various Reporters (voice) |
| A.J. Riebli III |
(voice) |
| Dan Scanlon |
(voice) |
| Stephen Schaffer |
(voice) |
| Ken Schretzmann |
(voice) |
| Bob Scott |
Additional Voices (voice) |
| Matt Staudt |
(voice) |
| Jay Ward |
(voice) |
| Jim Ward |
Various Reporters (voice) |
| Colette Whitaker |
(voice) |
